美国引领西方石油增产

14 06 2012

美国庞大的页岩储量开始重塑全球能源市场格局:不计欧佩克(Opec)成员国和前苏联加盟共和国,过去三年全球石油产量的净增长全部来自美国。

Do you feel surprised when seeing news like this?

I would say “Yes”. It’s not Norway, it’s not China, it’s US. Here is the full story: http://www.ftchinese.com/story/001045054#s=p (in Chinese)

This is the fact: “虽然美国依然是世界最大的石油进口国,但它目前的年进口量只占年需求量的45%,而2005年则为60%。”

Here is what the article says at the end:

水平钻井和水力压裂(最初应用于页岩气开发)技术的进步,使开发美国页岩油田和类似岩层成为可能,而之前这类开发活动不具有商业可行性。

Again, technology, creative technology – that’s the key for a nation to be outstanding.

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New era of DNA sequencing and related bioinformatics

9 12 2011

I can say the passed week is a week full of great news.

Wednesday (Nov 30, 2011)
“DNA Sequencing Caught in Deluge of Data” — You must want to read this article.

Monday (Dec 5, 2011)
UK will invest £75M for a new BIOINFORMATICS HUB in current EBI, as part of the ELIXIR project. I guess this must be within the framework of the HORIZON 2020, which the EU’s new programme for research and innovation running from 2014 to 2020 with an €80 billion budget. €80 billion!! OMG!

Tuesday (Dec 6, 2011)
The National Human Genome Research Institute (NHGRI), as part of NIH, announced to invest $416 million on research of using genomic data for medical clinical research, including rare inherit disease. Three genome sequencing centers are funded, including the Broad Institute, Genome Institute at Washington University, and Human Genome Sequencing Center, Baylor College of Medicine.

Whole-genome sequencing seems becoming more and more popular since it’s becoming cheaper and faster. Citing what the ELIXIR website says, “Modern sequencers are capable of analysing the equivalent of a human genome every 14 minutes at a cost of US $5,000.” We cannot imagine how easy to get a personal genome sequenced in next 5 years.

So, next question is: What would you do if it became possible to sequence the equivalent of a full human genome for only $1,000? This is the Question of the Year of Nature in 2007, when the whole-genome sequencing is still quite expensive. Personally I like the Ewan’s answer there: Full employment in bioinformatics. Think about it: if you can get your genome sequence in $1, what would you do to that 3,000,000,000 DNA nucleotides?
First of all, you may want to store it (or maybe not, since it’s too large). There are already companied coming out to store the DNA data, like the startup recently invested by Google Ventures, DNAnexus. But question is: who really wants to store all 3G data file, even though the 3G USB just costs less than $1? To only store the difference (between a particular genome and some reference genome), instead of every bit, might be the final solution.
Next, you want to see/visualize it. “Viewing your genomic data on iPhone” is one of such bleeding topics. I am quite serious, Illumina is working on the project with Apple, and even there are working Apps out already.
The most informative thing next is to analysis the data. It’s also the most challenging one. People including myself are working hard on it (That’s why the Uncle Sam invest money on it). Let’s think about this in a non-academic way. More and more companies smell the big cake (first let’s assume it’s a big cake), for example the genotyping-phenotype company like 23andme, the bioinformatics company like GenomeRequest, and just yesterday I read news about a new company called Spiral Genetics (who collect the open source software to do bioinformatics for customers, in a very smart way). Last week, Nature News blog reports the OpenSNP, a website (maybe a company next month) designed by several undergraduate students from U. Washington, they try to build the website to let people share their personal genotype data (from 23andme, deCODEme etc.). It’s a very cool idea!

OK. I know some people might be still questioning whether we need whole-genome sequencing. For individual research, it’s true that not every case needs whole-genome sequencing. But like from old phone to iphone, or from iphone to iphone3G, 4G, 4Gs… do you really need to change your iphone to Iphone 4Gs? You may not, or I am sure practically you don’t need at all. I am still using my wife’s old Nokia, no touch-screen, but very practical. Then why iphone 4Gs are so popular? Because it’s the trend! The lower cost and human’s desire/curiosity/greediness makes it popular. So the same for personal genome sequencing data. The only thing is to show this in an elegant way that even your grandma can understand. That’s the business!





祖国真是好样的!

3 11 2011

一早看到神州八号和天宫一号完美对接的新闻视频,甚是感动!祖国加油!!!

http://news.cntv.cn/china/20111103/115880.shtml





FW: 看问题的角度

27 05 2010

今天看到淬念留言,说中国各个阶层之间,更多的是冲突,是恶性的阶层歧视。这里,我想说说看问题的角度的事情。

以前在国内的时候,我也是看很多事情不顺眼,我也毫不犹豫的翻墙,为了户口的事情问候某些官员的直系母性亲属,也和很多人一样,以为美国的很多事情
会比中国好;出国以后,也经历了觉得什么都好,到发现其实也未必的阶段。我曾经因为能够去跟市政大楼里的法官聊天,解释一张停车罚单而觉得美国社会很合
理,也曾经因为被银行的接线员到处踢皮球,而觉得还是国内的银行其实更人性化一点。

那么,到底是中国好,还是美国好?这么多年过来,我发现,其实对于如此复杂的两个国家,个人其实是很难看到全貌的。就算是看到的这些方面,也有适合
自己的,和不适合自己的。与其简单的以好坏来定义一个国家,不如尽量中性的去描述,然后再看哪些方面是适合自己的,哪些是不适合的。之所以要绕这么一个弯
子,主要是不想被预先设定的态度蒙蔽了眼睛,忽略了可能的机会。

比如我前面一篇里面说的,中国各个阶层之间交流很多,交流可以是良性的,比如人之间的交往,贫困地区的学生通过考试和就业进入大城市的白领阶层(虽
然现在大城市的白领阶层,其实也不是富裕人群);当然交流也可以是恶性的,比如基于地域的歧视,基于财富的排斥等等。怎么看待这些事情,可以把它们看做是
人生的痛苦,可以把它们看做是社会的不公,当然也可以把它们,看成是新的机会。

股票市场上面有句话,叫只要价格有波动,就有机会。上次Freeman来,
我们也聊到,只要有问题,就有机会。从这个出发点来看,交流的机会多寡,是更重要的衡量标准,而善恶,则更多的是个人看问题的角度问题。我不是说善恶是不
重要的,善和恶更多的时候,是一个事物的两个方面,看到了一面,不要忽略同样重要的另一面,更重要的是,不要忽略了机会。

Filed under: 另一面 — 美人她爹 @ 9:37 pm

// 非常喜欢这篇博文的观点。虽然有些中庸,但是很积极。生命在于运动,这个世界也是动态的,只要动起来就会有机会。





James, 雄起!

15 05 2010
虽然xixi说凯尔特人队是我的凯尔特人队,但是詹姆斯的骑士队被淘汰了,早上又看到有关他母亲跟队友有染的传闻,真的希望James挺住,跟乐观的大鲨鱼一起留到下一个赛季打进总冠军!我一定买球票过来支持你!

加油!





成功不是一条单行道,而是一条绵延的长路

12 05 2010

Passion, Work, Focus, Push, Ideas, Improve, Serve, and Persist
成功的8个要素:激情,刻苦,专注,强迫?,点子,提高?,服务,坚持




游戏

5 05 2010
人只有充分是人的时候才游戏,人也只有在游戏的时候才充分是人。

--《非诚勿扰》点评上的一句话